Pesquisa | Secretaria de Estado da Saúde

1.

CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.

Huang, Shouxiong; Shahine, Adam; Cheng, Tan-Yun; Chen, Yi-Ling; Ng, Soo Weei; Balaji, Gautham R; Farquhar, Rachel; Gras, Stephanie; Hardman, Clare S; Altman, John D; Tahiri, Nabil; Minnaard, Adriaan J; Ogg, Graham S; Mayfield, Jacob A; Rossjohn, Jamie; Moody, D Branch.

Cell ; 186(21): 4583-4596.e13, 2023 10 12.

Artigo Inglês | MEDLINE | ID: mdl-37725977

2.

T cell antigen receptor recognition of antigen-presenting molecules.

Rossjohn, Jamie; Gras, Stephanie; Miles, John J; Turner, Stephen J; Godfrey, Dale I; McCluskey, James.

Annu Rev Immunol ; 33: 169-200, 2015.

Artigo Inglês | MEDLINE | ID: mdl-25493333

3.

Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan.

van de Sandt, Carolien E; Nguyen, Thi H O; Gherardin, Nicholas A; Crawford, Jeremy Chase; Samir, Jerome; Minervina, Anastasia A; Pogorelyy, Mikhail V; Rizzetto, Simone; Szeto, Christopher; Kaur, Jasveen; Ranson, Nicole; Sonda, Sabrina; Harper, Alice; Redmond, Samuel J; McQuilten, Hayley A; Menon, Tejas; Sant, Sneha; Jia, Xiaoxiao; Pedrina, Kate; Karapanagiotidis, Theo; Cain, Natalie; Nicholson, Suellen; Chen, Zhenjun; Lim, Ratana; Clemens, E Bridie; Eltahla, Auda; La Gruta, Nicole L; Crowe, Jane; Lappas, Martha; Rossjohn, Jamie; Godfrey, Dale I; Thomas, Paul G; Gras, Stephanie; Flanagan, Katie L; Luciani, Fabio; Kedzierska, Katherine.

Nat Immunol ; 24(11): 1890-1907, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37749325

4.

mRNA vaccine against malaria tailored for liver-resident memory T cells.

Ganley, Mitch; Holz, Lauren E; Minnell, Jordan J; de Menezes, Maria N; Burn, Olivia K; Poa, Kean Chan Yew; Draper, Sarah L; English, Kieran; Chan, Susanna T S; Anderson, Regan J; Compton, Benjamin J; Marshall, Andrew J; Cozijnsen, Anton; Chua, Yu Cheng; Ge, Zhengyu; Farrand, Kathryn J; Mamum, John C; Xu, Calvin; Cockburn, Ian A; Yui, Katsuyuki; Bertolino, Patrick; Gras, Stephanie; Le Nours, Jérôme; Rossjohn, Jamie; Fernandez-Ruiz, Daniel; McFadden, Geoffrey I; Ackerley, David F; Painter, Gavin F; Hermans, Ian F; Heath, William R.

Nat Immunol ; 24(9): 1487-1498, 2023 09.

Artigo Inglês | MEDLINE | ID: mdl-37474653

5.

Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.

Zhang, Wuji; Kedzierski, Lukasz; Chua, Brendon Y; Mayo, Mark; Lonzi, Claire; Rigas, Vanessa; Middleton, Bianca F; McQuilten, Hayley A; Rowntree, Louise C; Allen, Lilith F; Purcell, Ruth A; Tan, Hyon-Xhi; Petersen, Jan; Chaurasia, Priyanka; Mordant, Francesca; Pogorelyy, Mikhail V; Minervina, Anastasia A; Crawford, Jeremy Chase; Perkins, Griffith B; Zhang, Eva; Gras, Stephanie; Clemens, E Bridie; Juno, Jennifer A; Audsley, Jennifer; Khoury, David S; Holmes, Natasha E; Thevarajan, Irani; Subbarao, Kanta; Krammer, Florian; Cheng, Allen C; Davenport, Miles P; Grubor-Bauk, Branka; Coates, P Toby; Christensen, Britt; Thomas, Paul G; Wheatley, Adam K; Kent, Stephen J; Rossjohn, Jamie; Chung, Amy W; Boffa, John; Miller, Adrian; Lynar, Sarah; Nelson, Jane; Nguyen, Thi H O; Davies, Jane; Kedzierska, Katherine.

Nat Immunol ; 24(6): 966-978, 2023 06.

Artigo Inglês | MEDLINE | ID: mdl-37248417

6.

Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection.

Cooper, Lucy; Xu, Hui; Polmear, Jack; Kealy, Liam; Szeto, Christopher; Pang, Ee Shan; Gupta, Mansi; Kirn, Alana; Taylor, Justin J; Jackson, Katherine J L; Broomfield, Benjamin J; Nguyen, Angela; Gago da Graça, Catarina; La Gruta, Nicole; Utzschneider, Daniel T; Groom, Joanna R; Martelotto, Luciano; Parish, Ian A; O'Keeffe, Meredith; Scharer, Christopher D; Gras, Stephanie; Good-Jacobson, Kim L.

Immunity ; 2024 Mar 29.

Artigo Inglês | MEDLINE | ID: mdl-38593796

7.

Human CD8⁺ T cell cross-reactivity across influenza A, B and C viruses.

Koutsakos, Marios; Illing, Patricia T; Nguyen, Thi H O; Mifsud, Nicole A; Crawford, Jeremy Chase; Rizzetto, Simone; Eltahla, Auda A; Clemens, E Bridie; Sant, Sneha; Chua, Brendon Y; Wong, Chinn Yi; Allen, E Kaitlynn; Teng, Don; Dash, Pradyot; Boyd, David F; Grzelak, Ludivine; Zeng, Weiguang; Hurt, Aeron C; Barr, Ian; Rockman, Steve; Jackson, David C; Kotsimbos, Tom C; Cheng, Allen C; Richards, Michael; Westall, Glen P; Loudovaris, Thomas; Mannering, Stuart I; Elliott, Michael; Tangye, Stuart G; Wakim, Linda M; Rossjohn, Jamie; Vijaykrishna, Dhanasekaran; Luciani, Fabio; Thomas, Paul G; Gras, Stephanie; Purcell, Anthony W; Kedzierska, Katherine.

Nat Immunol ; 20(5): 613-625, 2019 05.

Artigo Inglês | MEDLINE | ID: mdl-30778243

8.

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

Wun, Kwok S; Reijneveld, Josephine F; Cheng, Tan-Yun; Ladell, Kristin; Uldrich, Adam P; Le Nours, Jérôme; Miners, Kelly L; McLaren, James E; Grant, Emma J; Haigh, Oscar L; Watkins, Thomas S; Suliman, Sara; Iwany, Sarah; Jimenez, Judith; Calderon, Roger; Tamara, Kattya L; Leon, Segundo R; Murray, Megan B; Mayfield, Jacob A; Altman, John D; Purcell, Anthony W; Miles, John J; Godfrey, Dale I; Gras, Stephanie; Price, David A; Van Rhijn, Ildiko; Moody, D Branch; Rossjohn, Jamie.

Nat Immunol ; 19(4): 397-406, 2018 04.

Artigo Inglês | MEDLINE | ID: mdl-29531339

9.

CD8⁺ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.

Lineburg, Katie E; Grant, Emma J; Swaminathan, Srividhya; Chatzileontiadou, Demetra S M; Szeto, Christopher; Sloane, Hannah; Panikkar, Archana; Raju, Jyothy; Crooks, Pauline; Rehan, Sweera; Nguyen, Andrea T; Lekieffre, Lea; Neller, Michelle A; Tong, Zhen Wei Marcus; Jayasinghe, Dhilshan; Chew, Keng Yih; Lobos, Christian A; Halim, Hanim; Burrows, Jacqueline M; Riboldi-Tunnicliffe, Alan; Chen, Weisan; D'Orsogna, Lloyd; Khanna, Rajiv; Short, Kirsty R; Smith, Corey; Gras, Stephanie.

Immunity ; 54(5): 1055-1065.e5, 2021 05 11.

Artigo Inglês | MEDLINE | ID: mdl-33945786

10.

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8⁺ T cell response.

Culshaw, Abigail; Ladell, Kristin; Gras, Stephanie; McLaren, James E; Miners, Kelly L; Farenc, Carine; van den Heuvel, Heleen; Gostick, Emma; Dejnirattisai, Wanwisa; Wangteeraprasert, Apirath; Duangchinda, Thaneeya; Chotiyarnwong, Pojchong; Limpitikul, Wannee; Vasanawathana, Sirijitt; Malasit, Prida; Dong, Tao; Rossjohn, Jamie; Mongkolsapaya, Juthathip; Price, David A; Screaton, Gavin R.

Nat Immunol ; 18(11): 1228-1237, 2017 Nov.

Artigo Inglês | MEDLINE | ID: mdl-28945243

11.

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.

Augusto, Danillo G; Murdolo, Lawton D; Chatzileontiadou, Demetra S M; Sabatino, Joseph J; Yusufali, Tasneem; Peyser, Noah D; Butcher, Xochitl; Kizer, Kerry; Guthrie, Karoline; Murray, Victoria W; Pae, Vivian; Sarvadhavabhatla, Sannidhi; Beltran, Fiona; Gill, Gurjot S; Lynch, Kara L; Yun, Cassandra; Maguire, Colin T; Peluso, Michael J; Hoh, Rebecca; Henrich, Timothy J; Deeks, Steven G; Davidson, Michelle; Lu, Scott; Goldberg, Sarah A; Kelly, J Daniel; Martin, Jeffrey N; Vierra-Green, Cynthia A; Spellman, Stephen R; Langton, David J; Dewar-Oldis, Michael J; Smith, Corey; Barnard, Peter J; Lee, Sulggi; Marcus, Gregory M; Olgin, Jeffrey E; Pletcher, Mark J; Maiers, Martin; Gras, Stephanie; Hollenbach, Jill A.

Nature ; 620(7972): 128-136, 2023 Aug.

Artigo Inglês | MEDLINE | ID: mdl-37468623

12.

αß T cell antigen receptor recognition of CD1a presenting self lipid ligands.

Birkinshaw, Richard W; Pellicci, Daniel G; Cheng, Tan-Yun; Keller, Andrew N; Sandoval-Romero, Maria; Gras, Stephanie; de Jong, Annemieke; Uldrich, Adam P; Moody, D Branch; Godfrey, Dale I; Rossjohn, Jamie.

Nat Immunol ; 16(3): 258-66, 2015 Mar.

Artigo Inglês | MEDLINE | ID: mdl-25642819

13.

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens.

de Jong, Annemieke; Cheng, Tan-Yun; Huang, Shouxiong; Gras, Stephanie; Birkinshaw, Richard W; Kasmar, Anne G; Van Rhijn, Ildiko; Peña-Cruz, Victor; Ruan, Daniel T; Altman, John D; Rossjohn, Jamie; Moody, D Branch.

Nat Immunol ; 15(2): 177-85, 2014 Feb.

Artigo Inglês | MEDLINE | ID: mdl-24362891

14.

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.

Van Braeckel-Budimir, Natalija; Gras, Stephanie; Ladell, Kristin; Josephs, Tracy M; Pewe, Lecia; Urban, Stina L; Miners, Kelly L; Farenc, Carine; Price, David A; Rossjohn, Jamie; Harty, John T.

Immunity ; 47(5): 835-847.e4, 2017 11 21.

Artigo Inglês | MEDLINE | ID: mdl-29150238

15.

Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase.

Ramos-Alonso, Lucía; Holland, Petter; Le Gras, Stéphanie; Zhao, Xu; Jost, Bernard; Bjørås, Magnar; Barral, Yves; Enserink, Jorrit M; Chymkowitch, Pierre.

Proc Natl Acad Sci U S A ; 120(4): e2210593120, 2023 01 24.

Artigo Inglês | MEDLINE | ID: mdl-36656860

16.

A conserved human T cell population targets mycobacterial antigens presented by CD1b.

Van Rhijn, Ildiko; Kasmar, Anne; de Jong, Annemieke; Gras, Stephanie; Bhati, Mugdha; Doorenspleet, Marieke E; de Vries, Niek; Godfrey, Dale I; Altman, John D; de Jager, Wilco; Rossjohn, Jamie; Moody, D Branch.

Nat Immunol ; 14(7): 706-13, 2013 Jul.

Artigo Inglês | MEDLINE | ID: mdl-23727893

17.

CD1d-lipid antigen recognition by the Î³Î´ TCR.

Uldrich, Adam P; Le Nours, Jérôme; Pellicci, Daniel G; Gherardin, Nicholas A; McPherson, Kirsty G; Lim, Ricky T; Patel, Onisha; Beddoe, Travis; Gras, Stephanie; Rossjohn, Jamie; Godfrey, Dale I.

Nat Immunol ; 14(11): 1137-45, 2013 Nov.

Artigo Inglês | MEDLINE | ID: mdl-24076636

18.

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.

Gras, Stephanie; Chadderton, Jesseka; Del Campo, Claudia M; Farenc, Carine; Wiede, Florian; Josephs, Tracy M; Sng, Xavier Y X; Mirams, Michiko; Watson, Katherine A; Tiganis, Tony; Quinn, Kylie M; Rossjohn, Jamie; La Gruta, Nicole L.

Immunity ; 45(4): 749-760, 2016 10 18.

Artigo Inglês | MEDLINE | ID: mdl-27717799

19.

Increasing HbA1c is associated with reduced CD8⁺ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus.

Hulme, Katina D; Tong, Zhen Wei Marcus; Rowntree, Louise C; van de Sandt, Carolien E; Ronacher, Katharina; Grant, Emma J; Dorey, Emily S; Gallo, Linda A; Gras, Stephanie; Kedzierska, Katherine; Barrett, Helen L; Short, Kirsty R.

Cell Mol Life Sci ; 81(1): 35, 2024 Jan 12.

Artigo Inglês | MEDLINE | ID: mdl-38214784

20.

Molecular insights into the HLA-B35 molecules' classification associated with HIV control.

Lobos, Christian A; Chatzileontiadou, Demetra Sm; Sok, Bonin; Almedia, Coral-Ann; Halim, Hanim; D'Orsogna, Lloyd; Gras, Stephanie.

Immunol Cell Biol ; 102(1): 34-45, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-37811811

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